Generic Cialis Online: Information and Application
Every man sooner or later is diagnosed erectile dysfunction - an erection failure, during which the rigidity, shape, and volume of the penis of a man does not allow him to perform sexual intercourse. These problems prevent the representatives of the stronger sex not only to conduct full-fledged sexual activity but also damage their mental health.
Often, erectile dysfunction is associated with a number of other diseases or mental abnormalities, and is less common as an autonomous ailment. However, today, there is an effective problem solution known as Cialis Generic.
Find out what this drug is and how it differs from the well-known Viagra.
What is Generic Cialis (Tadalafil) and How It Works? What does Cialis do?
Generic Cialis (Tadalafil) contains the following active substance: 1 tablet contains tadalafil 20 mg; auxiliary substances: lactose monohydrate, lactose monohydrate (dry spray), hydroxypropyl cellulose (EF very fine), croscarmellose sodium, sodium lauryl sulfate, microcrystalline cellulose (granulate 102), magnesium stearate (vegetable), dye mixture Opadry II yellow (32K12884), talcum.
Cialis is a popular remedy for increasing libido and treating the pathology associated with premature ejaculation. The drug was created as an alternative to Viagra.
Tadalafil is a reversible selective inhibitor of specific PDE-5 cGMP. When sexual stimulation causes local release of nitric oxide, inhibition of PDE-5 with tadalafil leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and the flow of blood to the tissues of the penis, which causes an erection. Tadalafil has no effect in the absence of sexual arousal.
In vitro studies have shown that generic Cialis is a selective inhibitor of PDE-5. PDE-5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of internal organs, in skeletal muscles, platelets, kidneys, lungs and the cerebellum. The effect of tadalafil on PDE-5 is more active than on other PDE. Generic Cialis (Tadalafil) is 10,000 times more potent for PDE-5 than for PDE-1, PDE-2, PDE-4 and PDE-7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and in other organs.
Tadalafil 10,000 times more actively blocks PDE-5 than PDE-3, an enzyme that is found in the heart and blood vessels. This selectivity for PDE-5 in comparison with PDE-3 is important, since PDE-3 is an enzyme involved in contraction of the heart muscle. In addition, tadalafil is approximately 700 times more active against PDE-5 than in relation to PDE-6, found in the retina and is responsible for photo-transmission. Tadalafil also exhibits an effect of 9000 times more potent on PDE-5 than its effect on PDE-8, PDE-9 and PDE-10 and 14 times more potent on PDE-5 than PDE-11. The distribution in tissues and the physiological effects of the inhibition of PDE-8-PDE-11 have not yet been elucidated.
Tadalafil improves an erection and increases the possibility of a full sexual intercourse. Tadalafil in healthy individuals does not cause a significant change in the SAD and DAD in comparison with placebo in the supine position (the average maximum decrease is 1.6 / 0.8 mm Hg, respectively) and in the standing position (the average maximum decrease is 0.2 / 4.6 mm Hg, respectively). Tadalafil does not cause a significant change in heart rate.
What is Cialis generic name?
The generic drug of "Cialis" is named "Tadalafil", there are two versions of the drug that is 20 mg of active ingredient per 1 tablet and 40 mg / tablet.
The efficacy and safety of Generic Cialis (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all severity levels when taking tadalafil 1 time per day. In studies on the primary efficacy of tadalafil at a dose of 5 mg, 62% and 69% of attempts at intercourse were successful compared with 34% and 39% of patients taking placebo. Admission of Generic Cialis in a dose of 5 mg significantly improved the erectile function within 24 hours between doses.
The mechanism of action of tadalafil in patients with BPH - the inhibition of PDE-5 by tadalafil, which leads to an increase in the concentration of cGMP in the cavernous body of the penis, is also observed in the smooth muscles of the prostate, bladder and blood vessels that supply them. Relaxation of smooth muscle vessels leads to an increase in blood perfusion in these organs and as a result - to reduce the severity of BPH symptoms. Relaxation of the smooth muscles of the prostate and bladder can further enhance vascular effects.
What is the Best Generic Cialis?
Cialis is one of the most popular drugs to increase sexual activity in men. Analogs of this medicine are also in demand. All because patients who are confronted with a disorder of sexual function, attract low price of generics. Despite the budgetary cost, generics of Cialis show good results if used in accordance with the instructions.
Many men ask themselves: which of these generics of Cialis is the best? Which generic pills is right for me?
Especially for you, we have prepared an overview of the most popular analogs of Cialis on the basis of tadalafil. You can look at the characteristics of each drug and make a choice.
So, we have presented you the list of the best generics of Cialis:
1. Generic Cialis;
2. Cialis Soft;
3. Professional Cialis;
4. Cialis Super Active +;
5. Cialis Jelly;
6. Apcalis SX.
For more information about each drug, you can study on the online pharmacy website or by consulting your physician.
Cialis vs Viagra - What is the Difference?
Cialis vs Viagra are similar in their action but have certain differences. Cialis tablets act like Viagra, but significantly exceed it in duration. They are quickly absorbed and act on the smooth muscles of the cavernous body, contributing to their relaxation and blood flow to the penis, resulting in an erection can occur during 36 hours, which makes the Cialis record for the duration of the action.
The influx of blood to the penis occurs under the action of acetylcholine and nitrogen oxide, synthesized by the nervous system. Phosphodiesterase lowers the concentration of these substances and stops the erection. Cialis belongs to inhibitors that selectively act on phosphodiesterase and cause its blocking.
But the medicine is not an aphrodisiac: excitation does not come from the drug, but from sexual stimulation. Therefore, when using Cialis vs Viagra, one does not have to worry that an erection will come at an inopportune time. At the end of sexual intercourse, erection passes naturally. The maximum effect of the drug manifests itself 2 hours after admission. Cialis drug can be taken before the alleged sexual contact, regardless of food intake while Viagra can't be combined with foods or alcohol. You can use Cialis together with alcoholic beverages and enjoy the same effect.
It is recommended to take 10-20 milligrams of Cialis. Exceed the maximum daily dose, which is 20 milligrams, is strictly prohibited. As for Viagra, its optimal dosage is 50 mg and the maximum dosage is 100mg. Thanks to the Cialis vs Viagra, an erection necessary for sexual intercourse is achieved, the man enjoys and satisfies the woman, acquires confidence in his abilities, which helps to improve mood and improve mental health.
It is worth buying Cialis for men experiencing erectile dysfunction as well as Viagra but remember that Cialis has a great advantage up to 36 hours of the effect. It will give an opportunity to have a full sexual intercourse. But pay attention to the fact that Cialis only treats impotence, providing the necessary erection, but does not increase sexual desire.
Cialis and Viagra Together
Cialis and Viagra are cures for erectile dysfunction. They belong to the group of inhibitors of phosphodiesterase type 5. Any of these drugs are allowed to take (regardless of dosage) no more than once within 24 hours. It is strictly forbidden to use Cialis and Viagra at the same time. Otherwise, you may experience severe side effects, such as a sharp drop in pressure, changes in color vision, temporary deterioration of hearing, etc. Before you start taking any medication, be sure to consult a doctor and read the instructions for use carefully.
6 Most common Mistakes in Taking Viagra and Cialis
1. Lack of sexual stimulation. A prerequisite for the inclusion of pills in the work is any kind of sexual stimulation, love games and the like.
2. Too small a dose of the drug. If you have not tried on the maximum allowable dose of the drug, you have no reason to declare its effectiveness. A similar error was committed by 31% of study participants. For most men, disillusioned with Viagra and Cialis, there is a fair formula: if the drug does not work - you need to increase the dose. In this case, the increase should occur within the limits stipulated in the instruction for the use of the drug.
3. Taking the drug after eating. About 20% of participants in the study regularly made another mistake: they took Viagra and Levitra immediately or after a short time after eating. The fact is that these two drugs are much more effective if they are taken on an empty stomach. It should be noted that this applies to Viagra and, to a lesser extent, Levitra. Cialis can be taken with food.
4. Too fast transition to sex. To achieve the expected effect of the use of drugs for potency, it is necessary to follow the instructions for the use of tablets. The instruction indicates the recommended time for the onset of an erection.
5. Unwillingness to experiment. In the beginning, try on yourself a minimum dose of the drug and even if it does not work, try at least once more. If you fail again, go to the next step and act this way until you find the optimal dose for you. The main thing - make more than one attempt with each dose, since one "failure" is not an indication that the pills do not work.
6. Excessive conservatism. If you want your experiments with PDE5 inhibitors to be truly fruitful - try more than one medicine. Looping on one single drug without trying anything else is the most common mistake that 40% of study participants allowed. The reaction of each patient to pharmacotherapy is strictly individual, and it is extremely difficult to predict it. However, be sure: generic Viagra, Cialis and Levitra, as well as the original drugs, do their work very effectively!
How Much Does Cialis Cost in the United States and Canada? Cialis Online Prices
Cialis cost depends on the dosage and the number of pills in the package. You can order Cialis 20 mg online at a cheaper price in comparison with the price that you will be offered at a local drugstore.
Cialis price per pill is $3.55 in Canadian drugstore if you buy a package of 10 pills only. Cialis cost will pleasantly surprise you if you take a decision to get 360 pills $1.42 per pill.
270 pills will cost you $389, where the price per pill is almost the same as in the package of 360 pills and it is $1.44.
As you can see, Cialis cost may vary and it is cheaper when you buy Cialis in a large package. You should choose the maximum package if you lead an active sexual life and want to save money on Cialis price.Cialis 20 mg - When is this Dosage Used?
The specialists determined the optimal daily dose of Cialis 20 mg - 1-a tablet, not more. The drug should be used at least half an hour before the onset of sexual intercourse. One of the most significant advantages of Cialis 20 mg is its prolonged effect. Its duration under ideally created conditions can last up to 36-48 hours. The maximum effectiveness of the action of Cialis 20 mg is noted directly during a natural sexual attraction to your partner.
There are certain limitations in taking Cialis 20 mg, more precisely in its dosage, in the presence of chronic kidney diseases, exacerbations of liver diseases, imbalance of the cardiovascular system or individual intolerance to the active substance of the proposed product.
From the clinical studies, serious cardiovascular events were reported, including myocardial infarction, sudden cardiac death, unstable angina pectoris, ventricular arrhythmia, cerebrovascular accident, transient ischemic attack, chest pain, heartbeat and tachycardia.
Most patients who experienced these side effects had risk factors for the cardiovascular system. At the same time, it is currently not possible to determine precisely whether the above phenomena are associated with risk factors, the use of Cialis should be limited if a man has heart problems to avoid risks.
Cialis 20 mg should be taken with caution by patients taking a-1 blockers, since in some patients simultaneous administration of these drugs can lead to symptomatic hypotension. Combined use of tadalafil and doxazosin is not recommended.
The dosage of 20 mg is recommended to men who don't have any other health problems, except ED. If you aren't sure that you are enough healthy to take the maximum dosage of Cialis 20 mg, then you'd better take the dosage of 10 mg. After checking the body reaction, you will be able to increase the dosage gradually.
Cialis Pills: How to Buy It Safely?
Cialis pills can be bought without a prescription online. Buy Cialis online from a reputable Canadian drugstore paying attention not only to the price range but to the number of positive reviews left by the customers with the same ED problems you have. Canadian pharmacies are well-known for their high-quality drugs offered at affordable prices if to buy Cialis online.
Buying Cialis pills on the Internet has a lot of advantages, among which the price is not the only one. You will enjoy the top-quality services, customer support, and a fast delivery, which can be even free if to purchase Cialis pills from the large pharmacy where there are often different special offers and discounts for both new customers and loyal clients.
It is easy to place an order online: just choose the necessary drug dosage, fill out a simple order form, and submit an order. In a couple of minutes, the manager will contact you to clarify some details and confirm the order. You will be able to choose the most suitable payment method and get Cialis pills at the most convenient time.